Jiang Lab, homeJiang Lab, home

Platform

Our instruments sit in our own lab at the Center for Virology and Vaccine Research, on the 10th floor of the Center for Life Science in Boston.

Together they carry one specimen from tissue processing through spatial protein and RNA maps to functional single-cell assays, all in house.

In the lab

  • The PhenoCycler-Fusion on a lab bench, next to its workstation.

    Akoya PhenoCycler-Fusion

    Whole-slide imaging of more than 50 proteins, two slides at a time.

  • Two CODEX fluidics units beside their Keyence microscopes.

    CODEX

    Two CODEX systems, each on a Keyence BZ-X810 microscope, for high-plex protein imaging.

  • The CosMx Spatial Molecular Imager.

    CosMx Spatial Molecular Imager

    Single-cell spatial transcriptomics on archival tissue.

  • The GeoMx Digital Spatial Profiler, with a sticker that reads Failure is not an option.

    GeoMx Digital Spatial Profiler

    Whole-transcriptome profiling of tissue regions chosen from tissue stains.

  • The LUMICKS z-Movi with its tubing and chip cleaning station.

    LUMICKS z-Movi

    Measures how strongly single immune cells bind their targets. We are a LUMICKS Center of Excellence.

  • The lab server rack.

    Computing

    Meet Boba Fett, Ceethreepo Plus and Darth Vader, our on-site compute and storage nodes, with >250 CPU threads, >4 TB of RAM, NVIDIA H200 GPUs and >1 PB of storage.

Also in the lab: a histology suite for tissue processing, a molecular biology and in situ hybridization bench, vacuum desiccators for tissue and slide storage, a 10x Genomics Visium CytAssist for whole-transcriptome spatial capture, including multi-omic approaches developed in house, and an Emulate organ-on-chip system for functional tissue models.

Join us

We are always looking for talented future colleagues on both the computational and experimental sides.

How to join the lab